Story continues from Spectacular Spider-Man 220. Terrific news! Mary Jane is pregnant! The Parkers are expecting a baby! But if the Amazing Spider-Man wants to live to see his child born, he must find a cure for the debilitating virus inside his body! Would the web-slinger be willing to stand arm-in-arm-in-arm with Doc Ock in order to be saved? Desperate times call for desperate measures! The doctor is in! Octopus style! Story concludes in Spectacular Spider-Man #221.